SWISS-PROT

 SWISS-PROT

SWISS-PROT is a secondary databases which provides detailed sequence annotation that includes structure, function, and protein family assignment. It was established in 1986.It is maintained collaboratively by SIB (Swiss Institute of Bioinformatics) and EBI/EMBL. Provides high-level annotations, including description of protein function, structure of protein domains, post-translational modifications, variants, etc. It aims to be minimally redundant. Swiss-Prot is linked to many other resources, including other sequence databases. The sequence data are mainly derived from TrEMBL, a database of translated nucleic acid sequences stored in the EMBL database. The annotation of each entry is carefully curated by human experts and thus is of good quality. The protein annotation includes function, domain structure, catalytic sites, cofactor binding, posttranslational modification, metabolic pathway information, disease association, and similarity with other sequences.

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